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Japan’s next-gen startups land in Singapore at X-HUB TOKYO 2025

Hosted by e27 with Deloitte and X-Hub Tokyo, the demo day brought ten cutting-edge Japanese startups to Singapore, connecting them with Southeast Asia’s investors, corporates, and innovation leaders.

On 7 October 2025, Innovation Crossover: X-HUB TOKYO – Singapore Demo Day 2025 brought together Southeast Asia’s key innovation stakeholders—corporates, VCs, and ecosystem enablers—to meet ten Japanese startups ready to expand into the region.

Hosted by e27, in partnership with X-HUB TOKYO, the demo day spotlighted cutting-edge innovation across health tech, climate tech, urban development, digital transformation, and mobility. The event served as a bridge between Japan’s emerging technologies and Southeast Asia’s fast-evolving markets, highlighting opportunities for collaboration and co‑creation.

From a high‑energy pitch session to small‑group networking, attendees had the chance to interact directly with founders behind Japan’s next wave of global startups and witness the region’s growing appetite for cross‑border innovation. Meet the ten startups below.

Health tech innovations redefining recovery and care

  • LIFESCAPES Inc. is developing breakthrough technology that restores motor function in stroke patients suffering from severe paralysis — offering new hope where existing treatments fall short.
  • I.W.G Inc.‘s DOCloud platform uses AI and cloud solutions to streamline collaboration between medical institutions, enhancing efficiency and data transparency in healthcare systems.

Also read: From funding wins to product launches: 10 SEA startups sharing milestones on e27

Climate tech innovators driving sustainability and smarter cities

  • WOTA CORP. is reimagining water access through decentralized water reuse systems that can be deployed anywhere, accelerating global sustainability through real-world pilots.
  • Jikantechno Inc. transforms agricultural and food waste into cost-effective industrial materials like silica and carbon, advancing sustainability and performance in manufacturing.
  • New Space Intelligence Inc. is a deep‑tech startup from Yamaguchi University that provides high‑precision satellite image calibration, enabling governments and enterprises to unlock new data-driven insights.
  • Reconnai Co., Ltd. offers AI-powered waste management solutions that transform environmental data into actionable insights, helping governments and businesses meet circular economy goals.
  • endophyte Inc. develops DSE fungi that enhance stress tolerance and nutrient uptake in plants, building sustainable urban greening ecosystems and driving co‑creation opportunities.

Data and mobility solutions powering smarter business and cities

  • CalTa Inc.‘s TRANCITY platform uses drone and smartphone video to generate 3D infrastructure models, streamlining inspections and improving safety for railways and urban systems.
  • SENRI Limited‘s mobile-first, AI-powered Salesforce automation platform for B2B field sales in Southeast Asia and Africa, helping companies improve sales performance and manage distributed teams effectively.
  • Kotozna Inc.‘s no-code GenAI platform enables multilingual digital engagement through AI chatbots and avatars, breaking down languagebarriers, removing the need for costly technical investments and automating customer/employee interactions

Also read: Beyond the code: Why AI literacy is the next great leadership skill for Southeast Asia

Building bridges for cross-border innovation

The event was a strategic bridge between Japan’s innovators and Southeast Asia’s opportunity landscape. Startups received valuable feedback from seasoned mentors including Nelson Ng (Good Karma), Aditya Mathur (Elev8 VC), Jack So (A*STAR), and Rashedun Nabi (e27). Their insights helped founders better understand the nuances of entering regional markets, from pilot testing to corporate partnerships.

Breakout networking sessions gave participants the chance to engage directly with startups, exchange insights, and explore potential collaborations across sectors. As part of their Onsite Program, the event aimed to strengthen connections between Japanese founders and Southeast Asia’s corporate, government, and investment communities—laying the groundwork for deeper engagement and tangible partnerships during SWITCH and future regional initiatives. Be sure to stop by their booths and say hello at SWITCH!

Keep the conversation going with Japan’s boldest new ventures

If you didn’t get a chance to meet your startup of interest, or want to continue the conversation, the connection lines remain open.

Tell us which startups you’d like to connect with: Fill out the connection form here

Whether you’re looking to partner, invest, or collaborate, your next opportunity might just be with one of Japan’s boldest new ventures.

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X-HUB TOKYO, sponsored by the Tokyo Metropolitan Government, serves as avital platform linking Tokyo to the global innovation ecosystem, accelerating startups that are poised to usher in a new era of innovation. The objective is to facilitate sustainable innovation by connecting both domestic and foreign startups with significant corporations and venture capitalists from around the world.

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The e27 team produced this article

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